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Anticorps Polyclonal de lapin anti-METTL8

METTL8 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31173-1-PBS

Synonymes

methyltransferase like 8

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using METTL8 Polyclonal antibody (31173-1-AP)

    WB analysis using 31173-1-AP (same clone as 31173-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31173-1-AP (METTL8 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31173-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of A431 cells using METTL8 Polyclonal antibody (31173-1-AP)

    IF Staining of A431 using 31173-1-AP (same clone as 31173-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed A431 cells using METTL8 antibody (31173-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 31173-1-PBS in a different storage buffer formulation.

Informations sur le produit

31173-1-PBS cible METTL8 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène METTL8 Protéine recombinante Ag34222
Nom complet methyltransferase like 8
Masse moléculaire calculée33 kDa
Poids moléculaire observé33~40 kDa
Numéro d’acquisition GenBankBC025250
Symbole du gène METTL8
Identification du gène (NCBI) 79828
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

METTL8 (methyltransferase-like protein 8) is an m3C methyltransferase that is best known for its mitochondrial role in installing m3C32 on mt-tRNAThr/Ser(UCN). METTL8 has proved to be a transcriptional target of STAT3 that mediates STAT3's functions in mESCs (PMID: 29706498). METTL8 has multiple splicing isoforms and can undergo sumoylation and associate with nuclear RNA-binding proteins to regulate R-loop formation on ribosomal DNA gene (presumably via its methyltransferase activity on m3C) (PMID: 38744809).

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