Anticorps Polyclonal de lapin anti-MEX3A

MEX3A Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30865-1-PBS

Synonymes

RKHD4, MEX 3A

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Galerie de données de validation

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  WB analysis using 30865-1-AP (same clone as 30865-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30865-1-AP (MEX3A antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30865-1-PBS in a different storage buffer formulation.

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  IF Staining of SH-SY5Y using 30865-1-AP (same clone as 30865-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using MEX3A antibody (30865-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 30865-1-PBS in a different storage buffer formulation.

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Informations sur le produit

30865-1-PBS cible MEX3A dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MEX3A Protéine recombinante Ag33619
• Nom complet: mex-3 homolog A (C. elegans)
• Masse moléculaire calculée: 54 kDa
• Poids moléculaire observé: 65-70 kDa
• Numéro d’acquisition GenBank: NM_001093725
• Symbole du gène: MEX3A
• Identification du gène (NCBI): 92312
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MEX3A is a member of the MEX3 family, which widely exists in mammalian cells and encodes four different genes, MEX3A, MEX3B, MEX3C, and MEX3D. The MEX3 protein of mammals is composed of two RNA-binding KH domains and a ring domain with E3 ubiquitin ligase activity at the C terminal. The ring finger domain endows human MEX3 protein the ability to regulate ubiquitination of target proteins and then influencing their protein stability and subcellular localization.MEX3A plays complex and diverse roles in the development of various cancers. MEX3A plays a pivotal role in the post-transcriptional procession of mRNA and gene expression. MEX3A gene expression may be closely connected with malignant tumor development and progression. In most literature, MEX3A detects molecular weights between 60 and 70kDa (PMID:33159833,37845346,36354374,35490173,34976441,33159833)

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