Anticorps Recombinant de lapin anti-MGL2

MGL2 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242983C6

N° de cat : 85876-1-PBS

Synonymes

Macrophage galactose N-acetyl-galactosamine specific lectin 2 , Macrophage galactose-type C-type lectin 2

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Galerie de données de validation

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  WB analysis using 85876-1-RR (same clone as 85876-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85876-1-RR (Mgl2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85876-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 85876-1-RR (same clone as 85876-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85876-1-RR (Mgl2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85876-1-PBS in a different storage buffer formulation.

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Informations sur le produit

85876-1-PBS cible MGL2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: MGL2 Protéine recombinante Eg2727
• Nom complet: macrophage galactose N-acetyl-galactosamine specific lectin 2
• Masse moléculaire calculée: 38 kDa
• Poids moléculaire observé: 40 kDa
• Numéro d’acquisition GenBank: NM_145137.2
• Symbole du gène: Mgl2
• Identification du gène (NCBI): 216864
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MGL2 is mainly expressed on immature dendritic cell (DCs) , tolerogenic DCs, type 2 DCs, and alternatively activated macrophages. MGL2 protein has carbohydrate-binding activity, specifically recognizing and binding to terminal GalNAc (n-acetyl 2-amino-2-deoxy-D-galactopyranose) residues, including the TN antigen (Galnac- αthrser) . This specific binding makes it play an important role in the recognition and processing of glycosylated pathogens, apoptotic cell fragments and tumor cells.

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