Anticorps Polyclonal de lapin anti-MGST3

MGST3 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20114-1-PBS

Synonymes

EC:1.11.1.-, EC:2.5.1.-, EC:4.4.1.20, Glutathione peroxidase MGST3, Glutathione S-transferase 3, mitochondrial

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Galerie de données de validation

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  WB analysis using 20114-1-AP (same clone as 20114-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20114-1-AP (MGST3 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20114-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20114-1-PBS cible MGST3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MGST3 Protéine recombinante Ag13932
• Nom complet: microsomal glutathione S-transferase 3
• Masse moléculaire calculée: 152 aa, 17 kDa
• Poids moléculaire observé: 16 kDa
• Numéro d’acquisition GenBank: BC000505
• Symbole du gène: MGST3
• Identification du gène (NCBI): 4259
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Microsomal glutathione transferase 3 (MGST3) is member of microsomal prostaglandin E synthases super family that exhibits diversified functions in eicosanoid and GSH metabolism. MGST3 expression level correlates with hippocampal size, and mutation of MGST3 contributes to spinal muscular dystrophy (PMID: 37760932). MGST3 KD did not alter intracellular reactive oxygen species level but selectively reduced the expression of apoptosis indicators which could be associated with the receptor of cysteinyl leukotrienes, the downstream metabolites of MGST3 in arachidonic acid pathway (PMID: 38971310).

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