Anticorps Polyclonal de lapin anti-CTAGE5

CTAGE5 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 31986-1-AP

Synonymes

cTAGE family member 5, CTAGE family member 5 ER export factor, CTAGE family, member 5, Cutaneous T-cell lymphoma-associated antigen 5, MEA11

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Galerie de données de validation

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  WB analysis using 31986-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31986-1-AP (CTAGE5 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules HepG2, cellules HuH-7

Dilution recommandée

• Western Blot (WB): WB : 1:1000-1:5000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

31986-1-AP cible CTAGE5 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CTAGE5 Protéine recombinante Ag34060
• Nom complet: CTAGE family, member 5
• Masse moléculaire calculée: 160 kDa
• Poids moléculaire observé: 240 kDa
• Numéro d’acquisition GenBank: BC130537
• Symbole du gène: CTAGE5
• Identification du gène (NCBI): 4253
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Cutaneous T-cell lymphoma-associated antigen 5 (CTAGE5, also known as MIA2) is a protein involved in the regulation of intracellular transport and secretion. It plays a crucial role in the trafficking of large cargo proteins, such as collagen VII, from the endoplasmic reticulum (ER) to the Golgi apparatus (PMID: 25202031; 27170179). CTAGE5 forms a complex with TANGO1, another cargo receptor, to facilitate the export of collagen VII from the ER (PMID: 21525241). This process is essential for the proper secretion of collagen and other large proteins, which are critical for maintaining tissue integrity and function. Additionally, CTAGE5 produces 240 and 120 kDa protein isoforms (PMID: 21807889).

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