Anticorps Polyclonal de lapin anti-MIER2

MIER2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17426-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 17426-1-AP (same clone as 17426-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17426-1-AP (MIER2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17426-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 17426-1-AP (same clone as 17426-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17426-1-AP (MIER2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17426-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17426-1-PBS cible MIER2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MIER2 Protéine recombinante Ag11491
• Nom complet: mesoderm induction early response 1, family member 2
• Masse moléculaire calculée: 545 aa, 60 kDa
• Poids moléculaire observé: 65-70 kDa
• Numéro d’acquisition GenBank: BC028203
• Symbole du gène: MIER2
• Identification du gène (NCBI): 54531
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Mesoderm induction early response 2 (MIER2) is a member of the MIER family of proteins, which is relatively conservative in evolution and includes three members: MIER1, MIER2, and MIER3. The MIER family is known to contribute to histone deacetylase (HDAC) activity and actively participate in histone deacetylation (PMID: 28046085; PMID: 38702028). In renal cell carcinoma, MIER2 represses PGC1A expression by recruiting HDAC1 to deacetylate P53 (PMID: 28046085).

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