Anticorps Polyclonal de lapin anti-MIER3

MIER3 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17543-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse uterus using 17543-1-AP (same clone as 17543-1-PBS)

  mouse uterus tissue were subjected to SDS PAGE followed by western blot with 17543-1-AP (MIER3 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17543-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse uterus using 17543-1-AP (same clone as 17543-1-PBS)

  mouse uterus tissue were subjected to SDS PAGE followed by western blot with 17543-1-AP (MIER3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17543-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17543-1-PBS cible MIER3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MIER3 Protéine recombinante Ag11604
• Nom complet: mesoderm induction early response 1, family member 3
• Masse moléculaire calculée: 522 aa, 59 kDa
• Poids moléculaire observé: 55 kDa
• Numéro d’acquisition GenBank: BC041348
• Symbole du gène: MIER3
• Identification du gène (NCBI): 166968
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The mesoderm induction early response (MIER) protein family is known as fibroblast growth factor (FGF)-regulated immediate-early protein family. Activated by FGF, MIER proteins may have a pivotal role in FGF-regulated cellular activities, indicating a potential influence in the progression of certain cancers [PMID:15117948]. MIER3 localizes to the nucleus and primarily functions as a transcriptional repressor. Rat mammary carcinoma susceptibility 1b (Mcs1b) is a quantitative trait locus on RN02 that confers decreased susceptibility when Copenhagen (COP)-resistant alleles are introgressed into a Wistar Furth (WF)-susceptible genome. MIER3 is a candidate Mcs1b gene [PMID:22993404].

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