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Anticorps Polyclonal de lapin anti-MINDY3

MINDY3 Polyclonal Antibody for IP, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IP, ELISA

Conjugaison

Non conjugué

N° de cat : 26478-1-PBS

Synonymes

C10orf97, CARP, Dermal papilla-derived protein 5, DERP5, Deubiquitinating enzyme MINDY-3

Galerie de données de validation

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  • Immunoprecipitation (IP) experiment of HCT 116 cells using MINDY3 Polyclonal antibody (26478-1-AP)

    IP experiment of HCT 116 using 26478-1-AP (same clone as 26478-1-PBS)

    IP result of anti-C10orf97 (IP:26478-1-AP, 4ug; Detection:26478-1-AP 1:1000) with HCT 116 cells lysate 1920 ug. This data was developed using the same antibody clone with 26478-1-PBS in a different storage buffer formulation.

Informations sur le produit

26478-1-PBS cible MINDY3 dans les applications de IP, ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène MINDY3 Protéine recombinante Ag23520
Nom complet chromosome 10 open reading frame 97
Poids moléculaire observé49 kDa
Numéro d’acquisition GenBankBC067799
Symbole du gène C10orf97
Identification du gène (NCBI) 80013
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MINDY3 (also known as FAM63B) is a deubiquitinating enzyme (DUB) localized to the endoplasmic reticulum and belongs to the MINDY family. This protein specifically recognizes and cleaves lysine 48 (K48)-linked ubiquitin chains, which serve as the primary signal targeting proteins for proteasomal degradation, thereby playing a critical role in regulating protein stability. Research indicates that MINDY3 influences various cellular processes through its deubiquitination activity, including endoplasmic reticulum-associated degradation (ERAD), cellular stress response, and cell cycle regulation. Dysregulation of its function is closely associated with pathological processes such as cancer and neurodegenerative diseases, making it a potential target for therapeutic research.

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