Anticorps Polyclonal de lapin anti-MMP11

MMP11 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30615-1-PBS

Synonymes

---

Galerie de données de validation

• 

  WB analysis using 30615-1-AP (same clone as 30615-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30615-1-AP (MMP11 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30615-1-PBS in a different storage buffer formulation.

• 

  IF Staining of A549 using 30615-1-AP (same clone as 30615-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells using MMP11 antibody (30615-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 30615-1-PBS in a different storage buffer formulation.

• 

  IF Staining of MCF-7 using 30615-1-AP (same clone as 30615-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using MMP11 antibody (30615-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 30615-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

30615-1-PBS cible MMP11 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MMP11 Protéine recombinante Ag31191
• Nom complet: matrix metallopeptidase 11 (stromelysin 3)
• Masse moléculaire calculée: 55 kDa
• Poids moléculaire observé: 50-55 kDa
• Numéro d’acquisition GenBank: NM_005940
• Symbole du gène: MMP11
• Identification du gène (NCBI): 4320
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Matrix metalloproteinase 11 (MMP11), also named stromelysin-3, is a member of the stromelysin subgroup belonging to MMPs superfamily. The role of MMP11 in cancer progression has been shown by several preclinical observations: its expression promotes tumor take in mice, homing of malignant epithelial cells, cancer progression by remodeling extracellular matrix, and antiapoptotic and antinecrotic effect on tumor cells (PMID: 19509157, 26892540). MMP11 has a calculated molecular mass of 55 kDa.

{{ptg:RelatedPrimaryAntibodies}}