Anticorps Polyclonal de lapin anti-MOCS1

MOCS1 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31550-1-PBS

Synonymes

KIAA0381, MIG11, MOCOD, MOCS1A, MOCS1B

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Galerie de données de validation

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  WB analysis using 31550-1-AP (same clone as 31550-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31550-1-AP (MOCS1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31550-1-PBS in a different storage buffer formulation.

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  IF Staining of Jurkat using 31550-1-AP (same clone as 31550-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed Jurkat cells using MOCS1 antibody (31550-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 31550-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31550-1-PBS cible MOCS1 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MOCS1 Protéine recombinante Ag35879
• Nom complet: molybdenum cofactor synthesis 1
• Masse moléculaire calculée: 70kDa
• Poids moléculaire observé: 40-43 kDa
• Numéro d’acquisition GenBank: NM_001075098
• Symbole du gène: MOCS1
• Identification du gène (NCBI): 4337
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MOCS1 (Molybdenum cofactor synthesis 1), also known as MOCS1A, MOCS1B, MOCOD, plays a crucial role in the biosynthesis of molybdenum cofactor and molybdopterin, which are essential for the activity of several key enzymes involved in carbon, nitrogen, and sulfur metabolism. MOCS1 produces two functional proteins, MOCS1A and MOCS1B, which follow different translocation routes before mitochondrial matrix import for cPMP biosynthesis involving both proteins (PMID: 31996372). MOCS1 was tumor suppressor gene affecting survival positively, while the other genes were oncogenes whose high expression was associated with poor survival (PMID: 37120564). The MOCS1 protein exists multiple isoforms.

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