Anticorps Monoclonal anti-MORC3

MORC3 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1E1E1

N° de cat : 68370-1-PBS

Synonymes

KIAA0136, MORC3, NXP2, ZCW5, ZCWCC3

---

Galerie de données de validation

• 

  WB analysis using 68370-1-Ig (same clone as 68370-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68370-1-Ig (MORC3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Lamin B1 Monoclonal antibody (HRP-66095) as loading control. This data was developed using the same antibody clone with 68370-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 68370-1-Ig (same clone as 68370-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68370-1-Ig (MORC3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Lamin B1 Monoclonal antibody (HRP-66095) as loading control. This data was developed using the same antibody clone with 68370-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

68370-1-PBS cible MORC3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: MORC3 Protéine recombinante Ag21867
• Nom complet: MORC family CW-type zinc finger 3
• Masse moléculaire calculée: 939 aa, 107 kDa
• Poids moléculaire observé: 130 kDa
• Numéro d’acquisition GenBank: BC132731
• Symbole du gène: MORC3
• Identification du gène (NCBI): 23515
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MORC3, also named as MORC family CW-type zinc finger protein 3 or NXP2, is a 939 amino acid protein, which contains 1 CW-type zinc finger. MORC3 localizes in the nucleus and are expressed in heart, placenta, skeletal muscle, brain, pancreas, lung, liver, but not kidney. MORC3 as Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism. Sumoylated MORC3-NBs can also associate with PML-NBs and recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity. It may be required for influenza A transcription during viral infection. The calculated molecular weight of MORC3 is a 107 kDa, but the Sumoylated MORC3 protein is about 130 kDa.

{{ptg:RelatedPrimaryAntibodies}}