Anticorps Polyclonal de lapin anti-MOSPD1

MOSPD1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32307-1-PBS

Synonymes

Motile sperm domain-containing protein 1

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Galerie de données de validation

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  WB analysis using 32307-1-AP (same clone as 32307-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32307-1-AP (MOSPD1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32307-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse cerebellum using 32307-1-AP (same clone as 32307-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 32307-1-AP (MOSPD1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 32307-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32307-1-PBS cible MOSPD1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MOSPD1 Protéine recombinante Ag37532
• Nom complet: motile sperm domain containing 1
• Masse moléculaire calculée: 24 kDa
• Poids moléculaire observé: 25 kDa
• Numéro d’acquisition GenBank: BC005700
• Symbole du gène: MOSPD1
• Identification du gène (NCBI): 56180
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MOSPD1, or Motile Sperm Domain-Containing Protein 1, is a protein that has been implicated in various biological processes. It is part of a family of proteins characterized by the presence of the major sperm protein domain and two transmembrane domains (PMID: 21792907). The protein is primarily located in the endoplasmic reticulum and Golgi apparatus, and it can also be found in the nucleus under certain conditions. MOSPD1 plays a significant role in the differentiation and proliferation of mesenchymal stem cells (MSCs). Studies have shown that MOSPD1-null embryonic stem cells exhibit impaired differentiation into various cell lineages, including osteoblasts and adipocytes, indicating its importance in MSC proliferation and differentiation (PMID: 26175344). Additionally, MOSPD1 is involved in the switch between mesenchymal and epithelial cells, suggesting its role in developmental regulation.

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