Anticorps Polyclonal de lapin anti-MRP1

MRP1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27825-1-PBS

Synonymes

---

Galerie de données de validation

• 

  WB analysis using 27825-1-AP (same clone as 27825-1-PBS)

  37°C incubated HeLa cells were subjected to SDS PAGE followed by western blot with 27825-1-AP (MRP1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27825-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 27825-1-AP (same clone as 27825-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 27825-1-AP (ABCC1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27825-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 27825-1-AP (same clone as 27825-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 27825-1-AP (ABCC1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27825-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

27825-1-PBS cible MRP1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MRP1 Protéine recombinante Ag27048
• Nom complet: ATP-binding cassette, sub-family C (CFTR/MRP), member 1
• Masse moléculaire calculée: 172 kDa
• Poids moléculaire observé: 180-190 kDa
• Numéro d’acquisition GenBank: NM_004996
• Symbole du gène: MRP1
• Identification du gène (NCBI): 4363
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Multidrug resistant-associated protein 1 (MRP1, also known as ABCC1) is a member of the ATP-binding cassette (ABC) transporter protein superfamily, subfamily C. MRP1 is overexpressed in cancers and contributes to the occurrence of multidrug resistance (MDR). Expression of MRP1 has been considered as a negative marker for the outcome of chemotherapy. Recently MRP1 has been reported to play a crucial role in Aβ clearance at the blood-brain barrier.

{{ptg:RelatedPrimaryAntibodies}}