Anticorps Monoclonal anti-MTCO2

• Phare
• Validé par KD/KO

MTCO2 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

10G14F4

N° de cat : 68527-1-PBS

Synonymes

COX2, 10G14F4, COII, COX 2, COXII

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Galerie de données de validation

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  WB analysis of 143B.TK.P0 using 68527-1-Ig (same clone as 68527-1-PBS)

  WB result of MTCO2 antibody (MTCO2; 1:1000; incubated at room temperature for 1.5 hours) with 143B and 143B.TK.ρ0 cell. 143B is wild-type cell line, 143B.TK.ρ0 is mtDNA deletion cell line. This data was developed using the same antibody clone with 68527-1-PBS in a different storage buffer formulation.

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  WB analysis using 68527-1-Ig (same clone as 68527-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68527-1-Ig (MTCO2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68527-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68527-1-PBS cible MTCO2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: cytochrome c oxidase II
• Masse moléculaire calculée: 26 kDa
• Poids moléculaire observé: 23-26 kDa
• Numéro d’acquisition GenBank: YP_003024029
• Symbole du gène: MTCO2
• Identification du gène (NCBI): 4513
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MTCO2, also named as COII, COXII, and COX2, belongs to the cytochrome c oxidase subunit 2 family. It is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. Defects in COX2 are a cause of mitochondrial complex IV deficiency (MT-C4D).

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