Anticorps Monoclonal anti-MTF2

MTF2 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain, Lapin, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2E5D5

N° de cat : 68713-1-PBS

Synonymes

dJ976O13.2, hPCl2, M96, MTF2, PCL2, Polycomb like protein 2, RP5 976O13.1

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Galerie de données de validation

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  WB analysis using 68713-1-Ig (same clone as 68713-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68713-1-Ig (MTF2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68713-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68713-1-PBS cible MTF2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, Lapin, rat, souris

• Réactivité: Humain, Lapin, rat, souris
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: MTF2 Protéine recombinante Ag9384
• Nom complet: metal response element binding transcription factor 2
• Masse moléculaire calculée: 536 aa, 61 kDa
• Poids moléculaire observé: 55 kDa, 60 kDa, 75 kDa
• Numéro d’acquisition GenBank: BC010013
• Symbole du gène: MTF2
• Identification du gène (NCBI): 22823
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MTF2, also named as Metal-response element-binding transcription factor 2, is a 593 amino acid protein. It exists several isoforms and the range of the molecular weight of isoforms are about 55-60 kDa and 29 kDa. MTF2 contains 2 PHD-type zinc fingers and belongs to the Polycomblike family. MTF2 acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex, leading to enhance PRC2 H3K27me3 methylation activity and regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation.

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