Anticorps Polyclonal de lapin anti-MTMR15/FAN1

• Phare
• Validé par KD/KO

MTMR15/FAN1 Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17600-1-PBS

Synonymes

MTMR15, EC:3.1.21.-, FAN1, FANCD2/FANCI-associated nuclease 1, Fanconi-associated nuclease 1

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Galerie de données de validation

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  WB analysis using 17600-1-AP (same clone as 17600-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17600-1-AP (MTMR15 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17600-1-PBS in a different storage buffer formulation.

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  WB analysis of human spleen using 17600-1-AP (same clone as 17600-1-PBS)

  human spleen tissue were subjected to SDS PAGE followed by western blot with 17600-1-AP (MTMR15 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17600-1-PBS in a different storage buffer formulation.

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  IP experiment of HeLa using 17600-1-AP (same clone as 17600-1-PBS)

  IP result of anti-MTMR15 (IP:17600-1-AP, 4ug; Detection:17600-1-AP 1:300) with HeLa cells lysate 2800 ug. This data was developed using the same antibody clone with 17600-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17600-1-PBS cible MTMR15/FAN1 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MTMR15/FAN1 Protéine recombinante Ag11651
• Nom complet: myotubularin related protein 15
• Masse moléculaire calculée: 60 kDa, 114 kDa
• Poids moléculaire observé: 63-68 kDa, 120-140 kDa
• Numéro d’acquisition GenBank: BC047882
• Symbole du gène: MTMR15
• Identification du gène (NCBI): 22909
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MTMR15, also named as FAN1 and KIAA1018, is a nuclease required for the repair of DNA interstrand cross-links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2. It is specifically involved in repair of ICL-induced DNA breaks by being required for efficient homologous recombination, probably in the resolution of homologous recombination intermediates. MTMR15 has some isoforms with MW 114 kDa and 60 kDa. The MW will be migrated to 120-140 kDa and 63-68 kDa with modification.

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