Anticorps Polyclonal de lapin anti-MTSS1

• Phare
• Validé par KD/KO

MTSS1 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13995-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 13995-1-AP (same clone as 13995-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 13995-1-AP (MTSS1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13995-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 13995-1-AP (same clone as 13995-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 13995-1-AP (MTSS1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13995-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 13995-1-AP (same clone as 13995-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 13995-1-AP (MTSS1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13995-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 13995-1-AP (same clone as 13995-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 13995-1-AP (MTSS1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13995-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 13995-1-AP (same clone as 13995-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 13995-1-AP (MTSS1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13995-1-PBS in a different storage buffer formulation.

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  IF Staining of MCF-7 using 13995-1-AP (same clone as 13995-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed MCF-7 cells using MTSS1 antibody (13995-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 13995-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13995-1-PBS cible MTSS1 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MTSS1 Protéine recombinante Ag5080
• Nom complet: metastasis suppressor 1
• Masse moléculaire calculée: 82 kDa
• Poids moléculaire observé: 82 kDa
• Numéro d’acquisition GenBank: BC023998
• Symbole du gène: MTSS1
• Identification du gène (NCBI): 9788
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MTSS1 (metastasis suppressor 1), also known as MIM (missing-in-metastasis), MIM-B, BEG4 (Basal cell carcinoma-enriched gene 4) or KIAA0429, is one of the defining members of the I-BAR family of negative membrane curvature-sensing proteins first identified as being deleted in metastatic bladder cancer. MTSS1 over-expression is associated with enhanced cell migration, resulting in tumorigenesis, invasion and metastasis (PMID: 27230279). It is reported that the expression of MTSS1 is associated with poor prognosis in various cancers,such as bladder, gastric, breast and so on (PMID: 32052679).

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