Anticorps Polyclonal de lapin anti-MTTP/MTP

MTTP/MTP Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 23940-1-PBS

Synonymes

MTTP, MTP

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Galerie de données de validation

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  WB analysis using 23940-1-AP (same clone as 23940-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 23940-1-AP (MTTP antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. Negative control: human skeletal muscle tissue, mouse kidney tissue, mouse skeletal muscle tissue, mouse spleen tissue. This data was developed using the same antibody clone with 23940-1-PBS in a different storage buffer formulation.

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Informations sur le produit

23940-1-PBS cible MTTP/MTP dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MTTP/MTP Protéine recombinante Ag21045
• Nom complet: microsomal triglyceride transfer protein
• Masse moléculaire calculée: 151aa,17 kDa; 894aa,99 kDa
• Poids moléculaire observé: 90-100 kDa
• Numéro d’acquisition GenBank: BC062696
• Symbole du gène: MTTP
• Identification du gène (NCBI): 4547
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MTTP, also known as MTP, belongs to the lipid transfer protein family and forms a heterodimeric complex with protein disulfide isomerase (PDI) to perform lipid transfer functions. MTTP is isolated as a soluble protein from the lumen of a microsomal fraction of liver and intestine. MTTP assembles triglycerides and apoB in the liver and intestine and subsequently produces apoB-containing lipoproteins. Deficiency in MTTP can cause abetalipoproteinemia, characterized by the absence of apoB-containing lipoproteins from the circulatory system(PMID: 10946006, 23475612).

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