Anticorps Monoclonal anti-MUC16/CA125

MUC16/CA125 Monoclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2B11B10

N° de cat : 60261-1-PBS

Synonymes

MUC16, MUC16,CA125, MUC-16, MUC 16, CA125

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Galerie de données de validation

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  IHC staining of human ovary tumor using 60261-1-Ig (same clone as 60261-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 60261-1-Ig (MUC16,CA125 Antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 60261-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary tumor using 60261-1-Ig (same clone as 60261-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 60261-1-Ig (MUC16,CA125 Antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 60261-1-PBS in a different storage buffer formulation.

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Informations sur le produit

60261-1-PBS cible MUC16/CA125 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: mucin 16, cell surface associated
• Masse moléculaire calculée: 1519 kDa
• Numéro d’acquisition GenBank: NM_024690
• Symbole du gène: MUC16
• Identification du gène (NCBI): 94025
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MUC16, also named as CA125, is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. It is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller "subunits" being described by some investigators. The antibody recognizes the C-term of MUC16.

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