Anticorps Polyclonal de lapin anti-MUPP1

MUPP1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22583-1-PBS

Synonymes

MPDZ

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Galerie de données de validation

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  WB analysis using 22583-1-AP (same clone as 22583-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 22583-1-AP (MUPP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22583-1-PBS in a different storage buffer formulation.

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Informations sur le produit

22583-1-PBS cible MUPP1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MUPP1 Protéine recombinante Ag18222
• Nom complet: multiple PDZ domain protein
• Masse moléculaire calculée: 2070 aa, 222 kDa
• Poids moléculaire observé: 250 kDa
• Numéro d’acquisition GenBank: BC140793
• Symbole du gène: MPDZ
• Identification du gène (NCBI): 8777
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The PDZ domain is a protein motif that mediates protein-protein interactions. MUPP1(multi-PDZ domain protein-1) has 13 PDZ domains, each containing the structural characteristics of a prototypic PDZ motif, but lacks a catalytic domain. MUPP1 belongs to the PDZ domain protein family and is a structural homologant of PATJ (PALS1-associated tight-linking protein) (PMID: 23880463). MUPP1 is a scaffold protein and plays an important role in cytoskeletal organization, cell polarity, and cell proliferation(PMID: 25662616). Mutations in MUPP1 are associated with congenital hydrocephalus(PMID: 23240096).

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