Anticorps Polyclonal de lapin anti-MYD88

MYD88 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29946-1-PBS

Synonymes

---

Galerie de données de validation

• 

  WB analysis using 29946-1-AP (same clone as 29946-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29946-1-AP (MYD88 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29946-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 29946-1-AP (same clone as 29946-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 29946-1-AP (MYD88 antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29946-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 29946-1-AP (same clone as 29946-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 29946-1-AP (MYD88 antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29946-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

29946-1-PBS cible MYD88 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons rat, souris

• Réactivité: rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MYD88 Protéine recombinante Ag30662
• Nom complet: myeloid differentiation primary response gene 88
• Masse moléculaire calculée: 34 kDa
• Poids moléculaire observé: 29-34 kDa
• Numéro d’acquisition GenBank: NM_010851
• Symbole du gène: Myd88
• Identification du gène (NCBI): 17874
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MYD88 is a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. MYD88 is the key adaptor protein for the interleukin-1 receptor (IL-1R) and most Toll-like receptors (TLRs), which are essential for innate immunity and pathogen-associated molecular pattern recognition. Mutations in the MyD88 gene lead to the development of cancer in humans and mice suggesting that MyD88 also plays a cell autonomous role in tissue homeostasis. MYD88 is detected in bone marrow.

{{ptg:RelatedPrimaryAntibodies}}