Anticorps Polyclonal de lapin anti-MYO1F

MYO1F Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28841-1-PBS

Synonymes

Unconventional myosin-If, Myosin-Ie, myosin IF, Myosin Ie

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Galerie de données de validation

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  WB analysis using 28841-1-AP (same clone as 28841-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 28841-1-AP (MYO1F antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28841-1-PBS in a different storage buffer formulation.

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  IF Staining of THP-1 using 28841-1-AP (same clone as 28841-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using MYO1F antibody (28841-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 28841-1-PBS in a different storage buffer formulation.

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Informations sur le produit

28841-1-PBS cible MYO1F dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: MYO1F Protéine recombinante Ag29899
• Nom complet: myosin IF
• Masse moléculaire calculée: 1098 aa, 125 kDa
• Poids moléculaire observé: 115-125 kDa
• Numéro d’acquisition GenBank: BC028071
• Symbole du gène: MYO1F
• Identification du gène (NCBI): 4542
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Myosin family members are proteins that hydrolyze ATP to generate force or directional movement along actin filaments and are implicated in the rearrangement of the cytoskeleton in several cell types. Myosin 1F (MYO1F), a long tailed class I myosin, is highly expressed in natural killer (NK) cells, macrophages, dendritic cells, and neutrophils. MYO1F plays a critical role in the mediating of signaling molecules "trafficking from membrane to cytoplasm," and this process is essential for the antifungal signaling pathway activation.

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