Anticorps Recombinant de lapin anti-MYO6

MYO6 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241251G11

N° de cat : 84085-3-PBS

Synonymes

241251G11, DFNA22, DFNB37, KIAA0389, myosin VI

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Galerie de données de validation

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  WB analysis using 84085-3-RR (same clone as 84085-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84085-3-RR (MYO6 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84085-3-PBS in a different storage buffer formulation.

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  WB analysis of LNCaP using 84085-3-RR (same clone as 84085-3-PBS)

  LNCaP cells were subjected to SDS PAGE followed by western blot with 84085-3-RR (MYO6 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84085-3-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP01001-1

  Cytometric bead array standard curve of MP01001-1, MYO6 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84085-3-PBS. Detection antibody: 84085-1-PBS. Standard: Ag24906. Range: 0.781-100 ng/ml.

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  Cytometric bead array standard curve of MP01001-3

  Cytometric bead array standard curve of MP01001-3, MYO6 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84085-2-PBS. Detection antibody: 84085-3-PBS. Standard: Ag24906. Range: 0.781-100 ng/ml.

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Informations sur le produit

84085-3-PBS cible MYO6 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: MYO6 Protéine recombinante Ag24906
• Nom complet: myosin VI
• Masse moléculaire calculée: 1285 aa, 149 kDa
• Poids moléculaire observé: 145-150 kDa
• Numéro d’acquisition GenBank: BC146764
• Symbole du gène: MYO6
• Identification du gène (NCBI): 4646
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MYO6, an actin-based motor protein, is the only myosin known to move toward the minus end of actin filaments. MYO6 is highly expressed in the inner and outer hair cells of the ear, retina, and polarized epithelial cells such as kidney proximal tubule cells and intestinal enterocytes. And it participates in a wide range of biological processes within cells, including clathrin-mediated endocytosis, vesicular membrane traffic, polarized secretion, and autophagy (PMID: 23620821; PMID: 28591580). Previous studies showed that MYO6 is upregulated in various types of cancer, and it has been widely reported to contribute to tumor cell migration and metastasis. Some articles indicate that MYO6 is associated with prostate cancer, lung cancer, human colorectal cancer and gastric cancer (PMID: 29022908).

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