Anticorps Recombinant de lapin anti-MYST2

MYST2 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251386C9

N° de cat : 86486-1-PBS

Synonymes

EC:2.3.1.48, HBO1, HBOa, Histone acetyltransferase KAT7, KAT 7

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Galerie de données de validation

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  WB analysis using 86486-1-RR (same clone as 86486-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86486-1-RR (MYST2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86486-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 86486-1-RR

  Biolayer interferometry (BLl) kinetic assays of 86486-1-RR against Human MYST2 were performed. The affinity constant is 1.94 nM.

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Informations sur le produit

86486-1-PBS cible MYST2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: MYST2 Protéine recombinante Ag4693
• Nom complet: MYST histone acetyltransferase 2
• Masse moléculaire calculée: 611 aa, 71 kDa
• Poids moléculaire observé: 71-75 kDa
• Numéro d’acquisition GenBank: BC032640
• Symbole du gène: MYST2
• Identification du gène (NCBI): 11143
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MYST2, also named as HBO1, HBOa MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2, belongs to the MYST (SAS/MOZ) family. It specifically represses AR mediated transcription. MYST2 is a candidate oncogene. It enhances the anchorage-independent growth of breast cancer cells.(PMID:19372580) MYST2 is a histone acetyltransferase (HAT) which could exert oncogenic function in breast cancer. It is an important downstream molecule of ERa, and ERK1/2 signaling pathway may involved in the expression of HBO1 increased by E2.

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