Anticorps Recombinant de lapin anti-MCP-1/CCL2

MCP-1/CCL2 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

230483F11

N° de cat : 83157-5-PBS

Synonymes

Ccl2, MCP1, MCP-1, chemokine (C C motif) ligand 2, CCL-2

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Galerie de données de validation

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  WB analysis of RAW 264.7 using 83157-5-RR (same clone as 83157-5-PBS)

  Un-treated, LPS and Brefeldin A treated RAW 264.7 cells were subjected to SDS PAGE followed by western blot with 83157-5-RR (Mcp1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83157-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83157-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83157-5-RR against Mouse MCP-1 were performed. The affinity constant is 60.5 pM.

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Informations sur le produit

83157-5-PBS cible MCP-1/CCL2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: chemokine (C-C motif) ligand 2
• Poids moléculaire observé: 16 kDa
• Numéro d’acquisition GenBank: NM-011333
• Symbole du gène: MCP-1/CCL2
• Identification du gène (NCBI): 20296
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Monocyte chemoattractant protein-1 (MCP-1/CCL2) is one of the key chemokines that regulate migration and infiltration of monocytes/macrophages. Both CCL2 and its receptor CCR2 have been demonstrated to be induced and involved in various diseases. Migration of monocytes from the blood stream across the vascular endothelium is required for routine immunological surveillance of tissues, as well as in response to inflammation.

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