Anticorps Monoclonal anti-CD11a

CD11a Monoclonal Antibody for Single Cell (Intra), Single Cell

Hôte / Isotype

Mouse / IgG1, kappa

Réactivité testée

Humain

Applications

Single Cell (Intra), Single Cell

Conjugaison

5CFLX Fluorescent Dye

CloneNo.

TS2/4

N° de cat : G65194-1-5C

Synonymes

CD11A, Integrin alpha L, ITGAL, LFA 1, LFA 1A, LFA1A

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Galerie de données de validation

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  Single Cell Sequencing experiment G65194-1-5C on Resting PBMC

  G65194-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

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  Single Cell Sequencing experiment G65194-1-5C on PBMC treated with 4hr LPS + TI

  G65194-1-5C was used to stain PBMC under 4hr LPS + TI treatment and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

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  Single Cell Sequencing experiment G65194-1-5C on Resting PBMC

  G65194-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Stain-Fix protocol.

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Applications testées

• Résultats positifs en Single Cell (Intra): 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product.
• Résultats positifs en Single Cell: 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product.

Dilution recommandée

• SINGLE CELL (INTRA): SINGLE CELL (INTRA) : <0.5ug/test
• SINGLE CELL: SINGLE CELL : <0.5ug/test

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

G65194-1-5C cible CD11a dans les applications de Single Cell (Intra), Single Cell et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1, kappa
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Lignée de CTL HLA-DR
• Nom complet: integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
• Masse moléculaire calculée: 129 kDa
• Numéro d’acquisition GenBank: BC008777
• Symbole du gène: CD11a
• Identification du gène (NCBI): 3683
• Conjugaison: 5CFLX Fluorescent Dye
• Forme: Liquide
• Tampon de stockage: PBS with 1mM EDTA and 0.09% sodium azide
• Conditions de stockage: 2-8°C Stable for one year after shipment. 20ul contiennent 0,1% de BSA.

Informations générales

CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).

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