Anticorps Monoclonal anti-CD21

CD21 Monoclonal Antibody for Single Cell (Intra), Single Cell

Hôte / Isotype

Mouse / IgG1, kappa

Réactivité testée

Humain

Applications

Single Cell (Intra), Single Cell

Conjugaison

5CFLX Fluorescent Dye

CloneNo.

BU32

N° de cat : G65198-1-5C

Synonymes

C3DR, CD21, Complement C3d receptor, Complement receptor type 2, CR2, EBV receptor, Epstein Barr virus receptor, SLEB9



Applications testées

Résultats positifs en Single Cell (Intra)10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product.
Résultats positifs en Single Cell10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product.

Dilution recommandée

ApplicationDilution
SINGLE CELL (INTRA)SINGLE CELL (INTRA) : <0.5ug/test
SINGLE CELLSINGLE CELL : <0.5ug/test
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

G65198-1-5C cible CD21 dans les applications de Single Cell (Intra), Single Cell et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Mouse / IgG1, kappa
Clonalité Monoclonal
Type Anticorps
Immunogène s/o
Nom complet complement component (3d/Epstein Barr virus) receptor 2
Masse moléculaire calculée 1092 aa, 119 kDa
Numéro d’acquisition GenBankBC136394
Symbole du gène CD21
Identification du gène (NCBI) 1380
Conjugaison 5CFLX Fluorescent Dye
Forme Liquide
Méthode de purification
Tampon de stockage PBS with 1mM EDTA and 0.09% sodium azide
Conditions de stockage2-8°C Stable for one year after shipment. 20ul contiennent 0,1% de BSA.

Informations générales

CD21, also known as complement receptor type 2 (CR2), complement C3d receptor, and Epstein-Barr virus receptor, is a transmembrane protein that contains a small cytoplasmic domain, a transmembrane region and an extracellular domain consisting of 15 tandem short consensus repeat sequences (PMID: 6230668; 2551147). It is expressed on B cells, follicular dendritic cells, thymocytes and a subset of peripheral T cells (PMID: 26119182). CD21 binds complement fragments C3d, C3dg and iC3b and acts as a receptor for the Epstein-Barr virus (PMID: 7753047). On B cells, together with CD19 and CD81, CD21 forms a complex that functions as a co-receptor to the BCR (PMID: 7542009). It is involved in B cells activation and functions.

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