Anticorps Monoclonal anti-CD21
CD21 Monoclonal Antibody for Single Cell (Intra), Single Cell
Hôte / Isotype
Mouse / IgG1, kappa
Réactivité testée
Humain
Applications
Single Cell (Intra), Single Cell
Conjugaison
5CFLX Fluorescent Dye
CloneNo.
BU32
N° de cat : G65198-1-5C
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en Single Cell (Intra) | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product. | 
| Résultats positifs en Single Cell | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product. | 
Dilution recommandée
| Application | Dilution | 
|---|---|
| SINGLE CELL (INTRA) | SINGLE CELL (INTRA) : <0.5ug/test | 
| SINGLE CELL | SINGLE CELL : <0.5ug/test | 
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Informations sur le produit
G65198-1-5C cible CD21 dans les applications de Single Cell (Intra), Single Cell et montre une réactivité avec des échantillons Humain
| Réactivité | Humain | 
| Hôte / Isotype | Mouse / IgG1, kappa | 
| Clonalité | Monoclonal | 
| Type | Anticorps | 
| Immunogène | s/o | 
| Nom complet | complement component (3d/Epstein Barr virus) receptor 2 | 
| Masse moléculaire calculée | 1092 aa, 119 kDa | 
| Numéro d’acquisition GenBank | BC136394 | 
| Symbole du gène | CD21 | 
| Identification du gène (NCBI) | 1380 | 
| Conjugaison | 5CFLX Fluorescent Dye | 
| Forme | Liquide | 
| Méthode de purification | |
| Tampon de stockage | PBS with 1mM EDTA and 0.09% sodium azide | 
| Conditions de stockage | 2-8°C Stable for one year after shipment. 20ul contiennent 0,1% de BSA. | 
Informations générales
CD21, also known as complement receptor type 2 (CR2), complement C3d receptor, and Epstein-Barr virus receptor, is a transmembrane protein that contains a small cytoplasmic domain, a transmembrane region and an extracellular domain consisting of 15 tandem short consensus repeat sequences (PMID: 6230668; 2551147). It is expressed on B cells, follicular dendritic cells, thymocytes and a subset of peripheral T cells (PMID: 26119182). CD21 binds complement fragments C3d, C3dg and iC3b and acts as a receptor for the Epstein-Barr virus (PMID: 7753047). On B cells, together with CD19 and CD81, CD21 forms a complex that functions as a co-receptor to the BCR (PMID: 7542009). It is involved in B cells activation and functions.



