Anticorps Monoclonal anti-CD86
CD86 Monoclonal Antibody for Single Cell (Intra), Single Cell
Hôte / Isotype
Mouse / IgG1, kappa
Réactivité testée
Humain
Applications
Single Cell (Intra), Single Cell
Conjugaison
5CFLX Fluorescent Dye
CloneNo.
BU63
N° de cat : G65165-1-5C
Synonymes
Galerie de données de validation
Applications testées
Résultats positifs en Single Cell (Intra) | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product. |
Résultats positifs en Single Cell | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product. |
Dilution recommandée
Application | Dilution |
---|---|
SINGLE CELL (INTRA) | SINGLE CELL (INTRA) : <0.5ug/test |
SINGLE CELL | SINGLE CELL : <0.5ug/test |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Informations sur le produit
G65165-1-5C cible CD86 dans les applications de Single Cell (Intra), Single Cell et montre une réactivité avec des échantillons Humain
Réactivité | Humain |
Hôte / Isotype | Mouse / IgG1, kappa |
Clonalité | Monoclonal |
Type | Anticorps |
Immunogène | Lignée cellulaire B-lymphoblastoïde ARH 77 |
Nom complet | CD86 molecule |
Masse moléculaire calculée | 329 aa, 38 kDa |
Numéro d’acquisition GenBank | BC040261 |
Symbole du gène | CD86 |
Identification du gène (NCBI) | 942 |
Conjugaison | 5CFLX Fluorescent Dye |
Forme | Liquide |
Méthode de purification | |
Tampon de stockage | PBS with 1mM EDTA and 0.09% sodium azide |
Conditions de stockage | 2-8°C Stable for one year after shipment. 20ul contiennent 0,1% de BSA. |
Informations générales
CD86 (also known as B7.2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response.