Anticorps Monoclonal anti-Cyclin D3
Cyclin D3 Monoclonal Antibody for Single Cell (Intra)
Hôte / Isotype
Mouse / IgG1
Réactivité testée
Humain
Applications
Single Cell (Intra)
Conjugaison
5CFLX Fluorescent Dye
CloneNo.
1F2C6
N° de cat : G66357-1-5C
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en Single Cell (Intra) | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product. |
Dilution recommandée
| Application | Dilution |
|---|---|
| SINGLE CELL (INTRA) | SINGLE CELL (INTRA) : <0.5ug/test |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Informations sur le produit
G66357-1-5C cible Cyclin D3 dans les applications de Single Cell (Intra) et montre une réactivité avec des échantillons Humain
| Réactivité | Humain |
| Hôte / Isotype | Mouse / IgG1 |
| Clonalité | Monoclonal |
| Type | Anticorps |
| Immunogène | Cyclin D3 Protéine recombinante Ag22825 |
| Nom complet | cyclin D3 |
| Masse moléculaire calculée | 33 kDa |
| Numéro d’acquisition GenBank | BC011616 |
| Symbole du gène | Cyclin D3 |
| Identification du gène (NCBI) | 896 |
| Conjugaison | 5CFLX Fluorescent Dye |
| Forme | Liquide |
| Méthode de purification | |
| Tampon de stockage | PBS with 1mM EDTA and 0.09% sodium azide |
| Conditions de stockage | 2-8°C Stable for one year after shipment. 20ul contiennent 0,1% de BSA. |
Informations générales
Cyclin D3 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activitiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.
