Anticorps Recombinant de lapin anti-ENO1
ENO1 Recombinant Antibody for Single Cell (Intra)
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain
Applications
Single Cell (Intra)
Conjugaison
5CFLX Fluorescent Dye
CloneNo.
2C20
N° de cat : G81478-1-5C
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en Single Cell (Intra) | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product. |
Dilution recommandée
| Application | Dilution |
|---|---|
| SINGLE CELL (INTRA) | SINGLE CELL (INTRA) : <0.5ug/test |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Informations sur le produit
G81478-1-5C cible ENO1 dans les applications de Single Cell (Intra) et montre une réactivité avec des échantillons Humain
| Réactivité | Humain |
| Hôte / Isotype | Lapin / IgG |
| Clonalité | Recombinant |
| Type | Anticorps |
| Immunogène | ENO1 Protéine recombinante Ag1692 |
| Nom complet | enolase 1, (alpha) |
| Masse moléculaire calculée | 47 kDa |
| Numéro d’acquisition GenBank | BC015641 |
| Symbole du gène | ENO1 |
| Identification du gène (NCBI) | 2023 |
| Conjugaison | 5CFLX Fluorescent Dye |
| Forme | Liquide |
| Méthode de purification | |
| Tampon de stockage | PBS with 1mM EDTA and 0.09% sodium azide |
| Conditions de stockage | 2-8°C Stable for one year after shipment. 20ul contiennent 0,1% de BSA. |
Informations générales
ENO1, also named as NNE, ENO1L1, MBPB1, MPB1 and MBP1, belongs to the enolase family. ENO1 is a metabolic enzyme involved in the synthesis of pyruvate. It also acts as a plasminogen receptor and mediates the activation of plasmin and extracellular matrix degradation. In tumor cells, ENO1 is up-regulated and supports the Warburg effect; it is expressed at the cell surface, where it promotes cancer invasion, and is subjected to a specific array of post-translational modifications, namely acetylation, methylation and phosphorylation. ENO1 overexpression and post-translational modifications could be of diagnostic and prognostic value in many cancer types. (PMID: 27814656). This antibody is specific to ENO1 and has no cross-reaction with ENO2 and ENO3.

