- Phare
- Validé par KD/KO
Anticorps Monoclonal anti-N-cadherin
N-cadherin Monoclonal Antibody for WB, IHC, IF-P, Cytometric bead array, Indirect ELISA
Hôte / Isotype
Mouse / IgG1
Réactivité testée
Humain, Lapin, porc, rat, souris
Applications
WB, IHC, IF-P, Cytometric bead array, Indirect ELISA
Conjugaison
Non conjugué
CloneNo.
1D8B3
N° de cat : 66219-1-PBS
Synonymes
Galerie de données de validation
Informations sur le produit
66219-1-PBS cible N-cadherin dans les applications de WB, IHC, IF-P, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain, Lapin, porc, rat, souris
Réactivité | Humain, Lapin, porc, rat, souris |
Hôte / Isotype | Mouse / IgG1 |
Clonalité | Monoclonal |
Type | Anticorps |
Immunogène | N-cadherin Protéine recombinante Ag4996 |
Nom complet | cadherin 2, type 1, N-cadherin (neuronal) |
Masse moléculaire calculée | 906 aa, 100 kDa |
Poids moléculaire observé | 130 kDa |
Numéro d’acquisition GenBank | BC036470 |
Symbole du gène | N-cadherin |
Identification du gène (NCBI) | 1000 |
Conjugaison | Non conjugué |
Forme | Liquide |
Méthode de purification | Purification par protéine G |
Tampon de stockage | PBS only |
Conditions de stockage | Store at -80°C. 20ul contiennent 0,1% de BSA. |
Informations générales
Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin), also known as CDH2 (cadherin 2), is a 130-kDa transmembrane protein and a classical member of the cadherin superfamily which also include E-, P-, R-, and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons, endothelial cells and cardiac myocytes (PMID: 11282032; 9508779; 8125202). N-cadherin has functions in early brain morphogenesis, synaptogenesis and synaptic plasticity (PMID: 23321619). The N-cadherin ectodomain can be cleaved, leading to the generation of a 90 kD N-terminal fragment (PMID: 16998833; 17028923).