Anticorps Monoclonal anti-NAGA

NAGA Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2A5F3

N° de cat : 67684-1-PBS

Synonymes

Alpha galactosidase B, D22S674, GALB, NAGA

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Galerie de données de validation

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  WB analysis using 67684-1-Ig (same clone as 67684-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67684-1-Ig (NAGA antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67684-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67684-1-PBS cible NAGA dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: NAGA Protéine recombinante Ag7225
• Nom complet: N-acetylgalactosaminidase, alpha-
• Masse moléculaire calculée: 47 kDa
• Poids moléculaire observé: 50 kDa
• Numéro d’acquisition GenBank: BC000095
• Symbole du gène: NAGA
• Identification du gène (NCBI): 4668
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NAGA belongs to the glycosyl hydrolase 27 family. It removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. It is required for the breakdown of glycolipids. Biosynthetic studies performed with cultured fibroblasts indicated that the human enzyme was synthesized as a 65 kDa glycosylated precursor which was processed to a mature 48-kDa lysosomal form; both the precursor and mature forms had high mannose type oligosaccharide chains, but only the precursor's mannose residues were phosphorylated. 90-117 kDa is a homodimer of NAGA.

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