Anticorps Recombinant de lapin anti-NAGK

NAGK Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251285C6

N° de cat : 86506-1-PBS

Synonymes

EC:2.7.1.-, EC:2.7.1.59, EC:2.7.1.60, GlcNAc kinase, GNK

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Galerie de données de validation

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  WB analysis using 86506-1-RR (same clone as 86506-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86506-1-RR (NAGK antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86506-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86506-1-PBS cible NAGK dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: NAGK Protéine recombinante Ag7034
• Nom complet: N-acetylglucosamine kinase
• Masse moléculaire calculée: 37 kDa
• Poids moléculaire observé: 37 kDa
• Numéro d’acquisition GenBank: BC001029
• Symbole du gène: NAGK
• Identification du gène (NCBI): 55577
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NAGK, also called N-acetylglucosamine kinase, or GlcNAc kinase, converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. NAGK can suppress the formation of α-syn A53T aggregates in neuronal and non-neuronal cells and suggest aggregation suppression is a general function of NAGK (PMID: 32796833). NAGK is broadly expressed in immune cells and has previously been described to contribute to the hexosamine biosynthetic salvage pathway (PMID: 36002575).

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