Anticorps Recombinant de lapin anti-NCAM1/CD56
NCAM1/CD56 Recombinant Antibody for Cytometric bead array, Indirect ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain
Applications
Cytometric bead array, Indirect ELISA
Conjugaison
Non conjugué
CloneNo.
240078B9
N° de cat : 83365-3-PBS
Synonymes
Galerie de données de validation
Informations sur le produit
83365-3-PBS cible NCAM1/CD56 dans les applications de Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain
| Réactivité | Humain |
| Hôte / Isotype | Lapin / IgG |
| Clonalité | Recombinant |
| Type | Anticorps |
| Immunogène | NCAM1/CD56 Protéine recombinante Eg31816 |
| Nom complet | neural cell adhesion molecule 1 |
| Masse moléculaire calculée | 95 kDa |
| Numéro d’acquisition GenBank | BC047244 |
| Symbole du gène | NCAM1 |
| Identification du gène (NCBI) | 4684 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par protéine A |
| Tampon de stockage | PBS only |
| Conditions de stockage | Store at -80°C. 20ul contiennent 0,1% de BSA. |
Informations générales
Neural cell adhesion molecule 1 (NCAM1, also known as CD56) is a cell adhesion glycoprotein of the immunoglobulin (Ig) superfamily. It is a multifunction protein involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM1 is expressed on human neurons, glial cells, skeletal muscle cells, NK cells and a subset of T cells, and the expression is observed in a wide variety of human tumors, including myeloma, myeloid leukemia, neuroendocrine tumors, Wilms' tumor, neuroblastoma, and NK/T cell lymphomas. Three major isoforms of NCAM1, with molecular masses of 120, 140, and 180 kDa, are generated by alternative splicing of mRNA (PMID: 9696812). The glycosylphosphatidylinositol (GPI)-anchored NCAM120 and the transmembrane NCAM140 and NCAM180 consist of five Ig-like domains and two fibronection-type III repeats (FNIII). All three forms can be posttranslationally modified by addition of polysialic acid (PSA) (PMID: 14976519). Several other isofroms have also been described (PMID: 1856291).
