Anticorps Recombinant de lapin anti-NCAM1/CD56
NCAM1/CD56 Recombinant Antibody for IF/ICC
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain
Applications
IF/ICC
Conjugaison
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
240078C9
N° de cat : CL488-83365-6
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en IF/ICC | cellules SH-SY5Y | 
Dilution recommandée
| Application | Dilution | 
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:200 | 
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Informations sur le produit
CL488-83365-6 cible NCAM1/CD56 dans les applications de IF/ICC et montre une réactivité avec des échantillons Humain
| Réactivité | Humain | 
| Hôte / Isotype | Lapin / IgG | 
| Clonalité | Recombinant | 
| Type | Anticorps | 
| Immunogène | Protéine recombinante | 
| Nom complet | neural cell adhesion molecule 1 | 
| Masse moléculaire calculée | 95 kDa | 
| Poids moléculaire observé | 160 kDa | 
| Numéro d’acquisition GenBank | BC047244 | 
| Symbole du gène | NCAM1 | 
| Identification du gène (NCBI) | 4684 | 
| Conjugaison | CoraLite® Plus 488 Fluorescent Dye | 
| Excitation/Emission maxima wavelengths | 493 nm / 522 nm | 
| Forme | Liquide | 
| Méthode de purification | Purification par protéine A | 
| Tampon de stockage | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA | 
| Conditions de stockage | Stocker à -20 °C. Éviter toute exposition à la lumière. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. | 
Informations générales
Neural cell adhesion molecule 1 (NCAM1, also known as CD56) is a cell adhesion glycoprotein of the immunoglobulin (Ig) superfamily. It is a multifunction protein involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM1 is expressed on human neurons, glial cells, skeletal muscle cells, NK cells and a subset of T cells, and the expression is observed in a wide variety of human tumors, including myeloma, myeloid leukemia, neuroendocrine tumors, Wilms' tumor, neuroblastoma, and NK/T cell lymphomas. Three major isoforms of NCAM1, with molecular masses of 120, 140, and 180 kDa, are generated by alternative splicing of mRNA (PMID: 9696812). The glycosylphosphatidylinositol (GPI)-anchored NCAM120 and the transmembrane NCAM140 and NCAM180 consist of five Ig-like domains and two fibronection-type III repeats (FNIII). All three forms can be posttranslationally modified by addition of polysialic acid (PSA) (PMID: 14976519). Several other isofroms have also been described (PMID: 1856291).
Protocole
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 NCAM1/CD56 antibody CL488-83365-6 | Download protocol | 
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols | 
