Anticorps Polyclonal de lapin anti-NCOR2

NCOR2 Polyclonal Antibody for ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IF, CoIP, ELISA

Conjugaison

Non conjugué

Publications

3

N° de cat : 20017-1-AP

Synonymes

CTG repeat protein 26, CTG26, N CoR2, NCOR2, Nuclear receptor corepressor 2, SMAP270, SMRT, SMRTE, SMRTE tau, T3 receptor associating factor, TNRC14, TRAC, TRAC 1, TRAC1

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Galerie de données de validation

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  WB analysis of HeLa using 20017-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 20017-1-AP (NCOR2 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours.

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  WB analysis of Jurkat using 20017-1-AP

  Jurkat cells were subjected to SDS PAGE followed by western blot with 20017-1-AP (NCOR2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Applications testées

Dilution recommandée

Application	Dilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 1 publications below
• IF: See 1 publications below
• CoIP: See 1 publications below

Informations sur le produit

20017-1-AP cible NCOR2 dans les applications de WB, IF, CoIP, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: nuclear receptor co-repressor 2
• Masse moléculaire calculée: 275 kDa
• Poids moléculaire observé: 180 kDa
• Numéro d’acquisition GenBank: NM_006312
• Symbole du gène: NCOR2
• Identification du gène (NCBI): 9612
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

NCOR2, also named as CTG26, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC-1, TRAC1 and SMAP270, belongs to the N-CoR nuclear receptor corepressors family. NCOR2 mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. The antibody recognizes all the isoforms of NCOR2. An about 180 KDa was also reported(PMID: 23081895).

Publications

Species	Application	Title
human	CoIP	Adv Sci (Weinh); Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer.; Authors - Shaliu Luo
human	WB	Cancer Sci; LncRNA MIR22HG inhibits growth, migration and invasion through regulating the miR-10a-5p/NCOR2 axis in hepatocellular carcinoma cells.; Authors - Yangjun Wu
	IF	Front Pharmacol; Analysis of Effect of Schisandra in the Treatment of Myocardial Infarction Based on Three-Mode Gene Ontology Network.; Authors - Siyao Hu