Anticorps Polyclonal de lapin anti-NDP

NDP Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 15380-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse testis using 15380-1-AP (same clone as 15380-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 15380-1-AP (NDP antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15380-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse eye using 15380-1-AP (same clone as 15380-1-PBS)

  mouse eye tissue were subjected to SDS PAGE followed by western blot with 15380-1-AP (NDP antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15380-1-PBS in a different storage buffer formulation.

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Informations sur le produit

15380-1-PBS cible NDP dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: NDP Protéine recombinante Ag4066
• Nom complet: Norrie disease (pseudoglioma)
• Masse moléculaire calculée: 15 kDa
• Poids moléculaire observé: 50-60 kDa
• Numéro d’acquisition GenBank: BC029901
• Symbole du gène: NDP
• Identification du gène (NCBI): 4693
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NDP, also named as EVR2, ND and Norrin, is a secreted regulatory protein that remains tightly associated with the extracellular matrix. Mutations in the NDP gene are associated with the Norrie disease. Signaling induced by the protein NDP regulates vascular development of vertebrate retina and controls important blood vessels in the ear. It binds with high affinity to Frizzled 4, and Frizzled 4 knockout mice exhibit abnormal vascular development of the retina. This antibody detects 11-15 kDa (monomer) and 48 kDa (polymers, refer: 25692504).

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