Anticorps Polyclonal de lapin anti-NESG1

NESG1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 21077-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 21077-1-AP (same clone as 21077-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21077-1-AP (NESG1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21077-1-PBS in a different storage buffer formulation.

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  WB analysis of rat testis using 21077-1-AP (same clone as 21077-1-PBS)

  rat testis tissue were subjected to SDS PAGE followed by western blot with 21077-1-AP (NESG1 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21077-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse testis using 21077-1-AP (same clone as 21077-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 21077-1-AP (NESG1 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21077-1-PBS in a different storage buffer formulation.

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Informations sur le produit

21077-1-PBS cible NESG1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: NESG1 Protéine recombinante Ag15257
• Nom complet: coiled-coil domain containing 19
• Masse moléculaire calculée: 551 aa, 66 kDa
• Poids moléculaire observé: 66 kDa
• Numéro d’acquisition GenBank: BC027874
• Symbole du gène: CCDC19
• Identification du gène (NCBI): 25790
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CCDC19, also named as NESG1, is specifically expressed in human nasopharynx and trachea, and decreased or absent in nasopharyngeal carcinoma (NPC) tissues and cell lines. In addition, the levels of NESG1 protein are significantly greater in the low-grade NPC tissues than that in the high-grade NPC tissues. NESG1 also significantly regulats the expression of cell cycle regulators CCNA1 and p21. NESG1 may act as a tumor suppressor by inhibiting cell proliferation, invasion and migration of NPC cells.

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