Anticorps Recombinant de lapin anti-NETO2

• Phare
• Validé par KD/KO

NETO2 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241451E10

N° de cat : 84222-2-PBS

Synonymes

241451E10, Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2, BTCL2, NEOT2, Neuropilin and tolloid-like protein 2

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Galerie de données de validation

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  WB analysis using 84222-2-RR (same clone as 84222-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84222-2-RR (NETO2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84222-2-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 84222-2-RR (same clone as 84222-2-PBS)

  WB result of NETO2 antibody (84222-2-RR; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-NETO2 transfected HEK-293 cells. This data was developed using the same antibody clone with 84222-2-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP01159-2

  Cytometric bead array standard curve of MP01159-2, NETO2 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84222-2-PBS. Detection antibody: 84222-4-PBS. Standard: Ag2971. Range: 0.156-20 ng/mL.

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  Affinity and Kinetic Characterization of 84222-2-RR

  Biolayer interferometry (BLl) kinetic assays of 84222-2-RR against Human NETO2 were performed. The affinity constant is 0.203 nM.

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Informations sur le produit

84222-2-PBS cible NETO2 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: NETO2 Protéine recombinante Ag2971
• Nom complet: neuropilin (NRP) and tolloid (TLL)-like 2
• Masse moléculaire calculée: 525 aa, 59 kDa
• Poids moléculaire observé: 59 kDa
• Numéro d’acquisition GenBank: BC012381
• Symbole du gène: NETO2
• Identification du gène (NCBI): 81831
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Neuropilin and tolloid-like 2 (NETO2), a member of the subfamily of CUB domain and LDLa-containing proteins, was identified as an auxiliary protein of neuronal kainate receptors (KARs) and played critical roles in regulating the functions of KARs. It was also able to bind to the active oligomeric form of K+-Cl− cotransporter (KCC2) to enhance its recycling in hippocampal neurons. Recently, elevated mRNA levels of NETO2 were detected in several types of tumors.

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