Anticorps Polyclonal de lapin anti-NEURL4

NEURL4 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 55345-1-PBS

Synonymes

Neuralized-like protein 4, Neuralized like protein 4, KIAA1787

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Galerie de données de validation

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  WB analysis using 55345-1-AP (same clone as 55345-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 55345-1-AP (NEURL4 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55345-1-PBS in a different storage buffer formulation.

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Informations sur le produit

55345-1-PBS cible NEURL4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: neuralized homolog 4 (Drosophila)
• Masse moléculaire calculée: 167 kDa
• Poids moléculaire observé: 166 kDa
• Numéro d’acquisition GenBank: NM_032442
• Symbole du gène: NEURL4
• Identification du gène (NCBI): 84461
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NEURL4, also known as KIAA1787, has 6 highly conserved neuralized homology repeats (NHRs), which are thought to mediate protein-protein interactions. NEURL4 localizes to the daughter centriole and prevents formation of ectopic microtubule-organizing centers. NEURL4 promotes CCP110 ubiquitination and proteasome-dependent degradation, maintaining normal centrosomal homeostasis and preventing the formation of abnormal microtubule tissue centers (MTOCs) by countering CP110 accumulation(PMID: 22441691, 22261722).

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