Anticorps Monoclonal anti-NEUROD2

NEUROD2 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, porc, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2C7B3

N° de cat : 68284-1-PBS

Synonymes

bHLHa1, NDRF, NeuroD related factor, NEUROD2, neurogenic differentiation 2

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Galerie de données de validation

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  WB analysis using 68284-1-Ig (same clone as 68284-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68284-1-Ig (NEUROD2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68284-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse cerebellum using 68284-1-Ig (same clone as 68284-1-PBS)

  mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 68284-1-Ig (NEUROD2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68284-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68284-1-PBS cible NEUROD2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, souris

• Réactivité: Humain, porc, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: NEUROD2 Protéine recombinante Ag26068
• Nom complet: neurogenic differentiation 2
• Masse moléculaire calculée: 41 kDa
• Poids moléculaire observé: 41-50 kDa
• Numéro d’acquisition GenBank: BC022481
• Symbole du gène: NEUROD2
• Identification du gène (NCBI): 4761
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NEUROD2 (Neurogenic differentiation factor 2), is transcriptional regulator that regulates early neuronal differentiation during development (PMID: 7754368). NeuroD2 is expressed in the postnatal cortex and mediate the activity-dependent refinement of thalamocortical axon terminals (PMID: 17453014). NeuroD2 is mainly involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Mutantions in NEUROD2 can cause neurodevelopmental disorders including intellectual disability and autism spectrum disorders (PMID: 34188164).

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