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Anticorps Polyclonal de lapin anti-NHE2

NHE2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25105-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using NHE2 Polyclonal antibody (25105-1-AP)

    WB analysis using 25105-1-AP (same clone as 25105-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25105-1-AP (NHE2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25105-1-PBS in a different storage buffer formulation.

Informations sur le produit

25105-1-PBS cible NHE2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène NHE2 Protéine recombinante Ag18801
Nom complet solute carrier family 9 (sodium/hydrogen exchanger), member 2
Masse moléculaire calculée 812 aa, 92 kDa
Poids moléculaire observé70 kDa
Numéro d’acquisition GenBankBC136377
Symbole du gène NHE2/SLC9A2
Identification du gène (NCBI) 6549
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NHE2, also known as SLC9A2, is a protein-coding gene mainly at the top of gastrointestinal epithelial cells. It mainly encodes a member of the sodium-hydrogen exchanger (NHE) protein family, which is localized to the apical membrane and is easily degraded by lysosomes, resulting in a short half-life. NHE2 is involved in sodium ion transport by exchanging intracellular hydrogen ions into external sodium ions, and helps in the regulation of cell pH and volume to eliminate acids produced by active metabolism or against adverse environmental conditions. NHE2 is widely distributed in tissues of the gastrointestinal tract, kidney, heart, testes, uterus, and adrenal glands (PMID: 37688782). The observed molecular weight of NHE2 is 70 kDa, which might be the unmodified form of NHE2 (PMID: 10444453, 10666043).

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