Anticorps Monoclonal anti-NK1.1 (CD161)

NK1.1 (CD161) Monoclonal Antibody for FC

Hôte / Isotype

Mouse / IgG2a, kappa

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

PK136

N° de cat : 65138-1-Ig

Synonymes

CD161, Klrb1a, Ly55a, NK1.1, NK1.1 (CD161), NKR P1A, Nkrp1 a, NKRP12, Nkrp1a



Applications testées

Résultats positifs en cytométrieC57BL/6 mouse splenocytes,

Dilution recommandée

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

65138-1-Ig cible NK1.1 (CD161) dans les applications de FC et montre une réactivité avec des échantillons souris

Réactivité souris
Hôte / Isotype Mouse / IgG2a, kappa
Clonalité Monoclonal
Type Anticorps
Immunogène Cellules NK-1+ de rate et de moelle osseuse de souris
Nom complet killer cell lectin-like receptor subfamily B member 1A
Numéro d’acquisition GenBankBC120707
Symbole du gène Klrb1a
Identification du gène (NCBI) 17057
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité
Tampon de stockage PBS with 0.09% sodium azide.
Conditions de stockageStore at 2-8°C. Stable for one year after shipment.

Informations générales

NK1.1 (CD161), also known as KLRB1 or NKR-P1A, is a type II transmembrane C-type lectin-like receptor and is expressed on the cell membrane as disulfide-linked homodimer (PMID: 8077657). It is expressed by the majority of NK cells and subsets of peripheral T cells, including both CD4+ and CD8+ T cells, and is expressed preferentially on adult T cells with a "memory" antigenic phenotype (PMID: 8077657; 22566826). Expression of CD161 correlates with the cytotoxic function of CD16+ NK cells, and ligation of CD161 with its ligand LLT1 inhibits NK cell cytotoxicity and cytokine secretion (PMID: 29686665).

Protocole

Product Specific Protocols
FC protocol for NK1.1 (CD161) antibody 65138-1-IgDownload protocol
Standard Protocols
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