Anticorps Polyclonal de lapin anti-NKAP

NKAP Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27437-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 27437-1-AP (same clone as 27437-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27437-1-AP (NKAP antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27437-1-PBS in a different storage buffer formulation.

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Informations sur le produit

27437-1-PBS cible NKAP dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: NKAP Protéine recombinante Ag26637
• Nom complet: NFKB activating protein
• Masse moléculaire calculée: 415 aa, 47 kDa
• Poids moléculaire observé: 47-50 kDa
• Numéro d’acquisition GenBank: BC015354
• Symbole du gène: NKAP
• Identification du gène (NCBI): 79576
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NKAP is a multifunctional nuclear protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. NKAP is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.

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