Anticorps Monoclonal anti-CD314/NKG2D

CD314/NKG2D Monoclonal Antibody for FC

Hôte / Isotype

Rat / IgG1, kappa

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

CX5

N° de cat : 65100-1-Ig

Synonymes

D6H12S2489E, Klrk1, NKG2 D, Nkg2d, NKG2D (CD314)

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Galerie de données de validation

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  FC experiment of C57 mouse splenic NK cells using 65100-1-Ig

  1X10^6 C57 mouse splenic NK cells were surface co-stained with FITC Anti-Mouse CD49b and 0.5 ug Anti-Mouse CD314/NKG2D (65100-1-Ig, Clone: CX5) or unstained (blank control). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: C57 mouse splenic NK cells,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

65100-1-Ig cible CD314/NKG2D dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Rat / IgG1, kappa
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Purified Mouse NKG2D protein
• Nom complet: killer cell lectin-like receptor subfamily K, member 1
• Numéro d’acquisition GenBank: BC057147
• Symbole du gène: CD314
• Identification du gène (NCBI): 27007
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Stable for one year after shipment.

Informations générales

CD314, also known as NKG2D or Killer cell lectin-like receptor subfamily K member 1 (KLRK1), is a type II lectin-like transmembrane stimulatory receptor (PMID: 8436421). In mice, CD314 is expressed on NK cells, activated CD8(+) T cells and macrophages, and subsets of TCR gamma delta (+) and NK1.1 (+) T cells (PMID: 12150888). Various subfamilies of MHC class I-related glycoproteins have been identified as the ligands for mouse CD314, including RAET1A, RAET1B, RAET1C, RAET1D, RAET1E, H60 and MULT1 (PMID: 31720075).

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