Anticorps Polyclonal de lapin anti-NKG7

NKG7 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 11532-1-PBS

Synonymes

G CSF induced gene 1 protein, G-CSF-induced gene 1 protein, GIG 1 protein, GIG1, GIG-1 protein

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Galerie de données de validation

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  WB analysis using 11532-1-AP (same clone as 11532-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 11532-1-AP (NKG7 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11532-1-PBS in a different storage buffer formulation.

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  IP experiment of NK-92 using 11532-1-AP (same clone as 11532-1-PBS)

  IP result of anti-NKG7 (IP:11532-1-AP, 4ug; Detection:11532-1-AP 1:1000) with NK-92 cells lysate 1120 ug. This data was developed using the same antibody clone with 11532-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 11532-1-AP (same clone as 11532-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 11532-1-AP (NKG7 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11532-1-PBS in a different storage buffer formulation.

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Informations sur le produit

11532-1-PBS cible NKG7 dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: NKG7 Protéine recombinante Ag2117
• Nom complet: natural killer cell group 7 sequence
• Masse moléculaire calculée: 165 aa, 18 kDa
• Poids moléculaire observé: 18 kDa
• Numéro d’acquisition GenBank: BC015759
• Symbole du gène: NKG7
• Identification du gène (NCBI): 4818
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Natural killer cell granule protein 7 (NKG7) regulates lymphocyte granule exocytosis and downstream inflammation in a broad range of diseases. NKG7 expressed by CD4+ and CD8+ T cells were key in promoting inflammation during visceral leishmaniasis and malaria-two important parasitic diseases. It is expressed by natural killer cells and is critical for controlling cancer initiation, growth, and metastasis (PMID: 32839608; 8458737). In brief, NKG7 is a necessary T-cell intrinsic factor for the cytotoxic function of CD8+ T cells and established NKG7 as a new therapeutic target for cancer immunotherapy (PMID: 34911739).

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