Anticorps Polyclonal de lapin anti-NKp46/NCR1

NKp46/NCR1 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31984-1-PBS

Synonymes

Ncr1, Natural killer cell p46-related protein, mNKp46, Lymphocyte antigen 94, Ly94

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Galerie de données de validation

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  IHC staining of mouse spleen using 31984-1-AP (same clone as 31984-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse spleen tissue slide using 31984-1-AP (NKp46/NCR1 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31984-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse spleen using 31984-1-AP (same clone as 31984-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse spleen tissue slide using 31984-1-AP (NKp46/NCR1 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31984-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31984-1-PBS cible NKp46/NCR1 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: natural cytotoxicity triggering receptor 1
• Masse moléculaire calculée: 37kDa
• Numéro d’acquisition GenBank: NM_010746.3
• Symbole du gène: NKp46/NCR1
• Identification du gène (NCBI): 17086
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NKp46, also known as NCR1 or CD335, is an Ig-like superfamily cell surface receptor that is highly conserved in mammals (PMID: 22021440). NKp46 is a type I transmembrane glycoprotein consisting of two extracellular Ig-like domains, a transmembrane domain, and an intracellular tail (PMID: 9730896). It is expressed on NK cells, rare T-cell subsets and a mucosal population of NKp46+ innate lymphoid cells (PMID: 9730896; 22021440). NKp46 is the major triggering receptor involved in the natural cytotoxicity (PMID: 10359120; 10092106; 15356098).

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