Anticorps Recombinant de lapin anti-NKp46/NCR1

NKp46/NCR1 Recombinant Antibody for FC

Hôte / Isotype

Rat / IgG2a

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

29A1.4

N° de cat : 65667-1-PBS

Synonymes

Ncr1, Activating receptor 1, CD335, Ly94, Lymphocyte antigen 94

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Galerie de données de validation

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  FC experiment of mouse splenocytes using 65667-1-TR (same clone as 65667-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.5 ug Anti-Mouse CD335 (29A1.4) Rat IgG2a RecAb (65667-1-TR, Clone:29A1.4) or Rat IgG2a Isotype Control Recombinant Antibody (98427-1-TR, Clone: 250862A1), and FITC anti-Rat IgG2a antibody. Cells were then stained with CoraLite® Plus 647 Anti-Mouse CD49b (HMA2) (CL647-65245, Clone: HMA2). Cells were not fixed. This data was developed using the same antibody clone with 65667-1-PBS in a different storage buffer formulation.

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  FC experiment of mouse splenocytes using 65667-1-TR (same clone as 65667-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.5 ug Anti-Mouse CD335 (29A1.4) Rat IgG2a RecAb (65667-1-TR, Clone: 29A1.4) (red) or Rat IgG2a Isotype Control Recombinant Antibody (98427-1-TR, Clone: 250862A1) (blue), and FITC anti-Rat IgG2a antibody. Cells were not fixed. This data was developed using the same antibody clone with 65667-1-PBS in a different storage buffer formulation.

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Informations sur le produit

65667-1-PBS cible NKp46/NCR1 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Rat / IgG2a
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: s/o
• Nom complet: natural cytotoxicity triggering receptor 1
• Numéro d’acquisition GenBank: BC042788
• Symbole du gène: NKp46/NCR1
• Identification du gène (NCBI): 17086
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

NKp46, also known as NCR1 or CD335, is an Ig-like superfamily cell surface receptor that is highly conserved in mammals (PMID: 22021440). NKp46 is a type I transmembrane glycoprotein consisting of two extracellular Ig-like domains, a transmembrane domain, and an intracellular tail (PMID: 9730896). It is expressed on NK cells, rare T-cell subsets and a mucosal population of NKp46+ innate lymphoid cells (PMID: 9730896; 22021440). NKp46 is the major triggering receptor involved in the natural cytotoxicity (PMID: 10359120; 10092106; 15356098).

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