Anticorps Recombinant de lapin anti-NKp46/NCR1

NKp46/NCR1 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241804A12

N° de cat : 98198-1-RR

Synonymes

Ncr1, mNKp46, Lymphocyte antigen 94, Ly94, CD335

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Galerie de données de validation

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  FC experiment of mouse splenocytes using 98198-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse NKp46/NCR1 Rabbit Recombinant Antibody (98198-1-RR, Clone: 241804A12) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Mouse CD49b. Cells were not fixed.

• 

  FC experiment of mouse splenocytes using 98198-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse NKp46/NCR1 Rabbit Recombinant Antibody (98198-1-RR, Clone: 241804A12)(red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

• 

  Affinity and Kinetic Characterization of 98198-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98198-1-RR against Mouse NKp46/NCR1 were performed. The affinity constant is below 1 pM.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98198-1-RR cible NKp46/NCR1 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: natural cytotoxicity triggering receptor 1
• Masse moléculaire calculée: 37kDa
• Numéro d’acquisition GenBank: NM_010746.3
• Symbole du gène: NKp46/NCR1
• Identification du gène (NCBI): 17086
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

NKp46, also known as NCR1 or CD335, is an Ig-like superfamily cell surface receptor that is highly conserved in mammals (PMID: 22021440). NKp46 is a type I transmembrane glycoprotein consisting of two extracellular Ig-like domains, a transmembrane domain, and an intracellular tail (PMID: 9730896). It is expressed on NK cells, rare T-cell subsets and a mucosal population of NKp46+ innate lymphoid cells (PMID: 9730896; 22021440). NKp46 is the major triggering receptor involved in the natural cytotoxicity (PMID: 10359120; 10092106; 15356098).

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