Anticorps Recombinant de lapin anti-NKp46/NCR1

NKp46/NCR1 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

CoraLite®594 Fluorescent Dye

CloneNo.

242549D12

N° de cat : CL594-98340

Synonymes

242549D12, CD335, hNKp46, LY94, Natural killer cell p46-related protein

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Galerie de données de validation

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  FC experiment of human PBMCs using CL594-98340

  1x10^6 human PBMCs were surface stained with CoraLite® Plus 488 Anti-Human NCAM1/CD56, and 5 ul CoraLite®594 Anti-Human NKp46/NCR1 Rabbit RecAb (CL594-98340, Clone: 242549D12) or CoraLite®594 Rabbit IgG Isotype Control RecAb (CL594-98136, Clone: 240953C9). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  FC experiment of human PBMCs using CL594-98340

  1x10^6 human PBMCs were surface stained with 5 ul CoraLite®594 Anti-Human NKp46/NCR1 Rabbit RecAb (CL594-98340, Clone: 242549D12) (red) or CoraLite®594 Rabbit IgG Isotype Control RecAb (CL594-98136, Clone: 240953C9) (blue). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: CMSP humaines

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL594-98340 cible NKp46/NCR1 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: NKp46/NCR1 Protéine recombinante Eg1364
• Nom complet: natural cytotoxicity triggering receptor 1
• Masse moléculaire calculée: 34kDa
• Symbole du gène: NCR1
• Identification du gène (NCBI): 9437
• Conjugaison: CoraLite®594 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 588 nm / 604 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

NKp46, also known as NCR1 or CD335, is an Ig-like superfamily cell surface receptor that is highly conserved in mammals (PMID: 22021440). NKp46 is a type I transmembrane glycoprotein consisting of two extracellular Ig-like domains, a transmembrane domain, and an intracellular tail (PMID: 9730896). It is expressed on NK cells, rare T-cell subsets and a mucosal population of NKp46+ innate lymphoid cells (PMID: 9730896; 22021440). NKp46 is the major triggering receptor involved in the natural cytotoxicity (PMID: 10359120; 10092106; 15356098).

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